node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KOG67347.1 | KOG69637.1 | ADK78_41100 | ADK78_33285 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.811 |
KOG67347.1 | KOG70971.1 | ADK78_41100 | ADK78_26855 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
KOG67347.1 | KOG73315.1 | ADK78_41100 | ADK78_17155 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
KOG67347.1 | KOG74295.1 | ADK78_41100 | ADK78_14730 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
KOG67347.1 | KOG76187.1 | ADK78_41100 | ADK78_11310 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.474 |
KOG67347.1 | KOG77820.1 | ADK78_41100 | ADK78_08500 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
KOG67347.1 | KOG81568.1 | ADK78_41100 | ADK78_03940 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phenylhydantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
KOG67347.1 | KOG82242.1 | ADK78_41100 | ADK78_03205 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
KOG67347.1 | kgd | ADK78_41100 | ADK78_04325 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |
KOG67347.1 | pdxS | ADK78_41100 | ADK78_19255 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.852 |
KOG69637.1 | KOG67347.1 | ADK78_33285 | ADK78_41100 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.811 |
KOG69637.1 | KOG73315.1 | ADK78_33285 | ADK78_17155 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
KOG69637.1 | KOG74295.1 | ADK78_33285 | ADK78_14730 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.895 |
KOG69637.1 | KOG76187.1 | ADK78_33285 | ADK78_11310 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.650 |
KOG69637.1 | KOG77820.1 | ADK78_33285 | ADK78_08500 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.645 |
KOG69637.1 | KOG82242.1 | ADK78_33285 | ADK78_03205 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
KOG69637.1 | pdxS | ADK78_33285 | ADK78_19255 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.782 |
KOG70971.1 | KOG67347.1 | ADK78_26855 | ADK78_41100 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.918 |
KOG70971.1 | KOG73315.1 | ADK78_26855 | ADK78_17155 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KOG70971.1 | KOG74295.1 | ADK78_26855 | ADK78_14730 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.898 |