STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (377 aa)    
Predicted Functional Partners:
KOG72316.1
Peptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KOG72329.1
Alanine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.998
KOG72313.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
pheT
phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.993
KOG72319.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.986
KOG68900.1
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.982
rsmA
16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.977
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.975
KOG72566.1
rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.973
KOG72310.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.971
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.