STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOG68546.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.998
KOG68547.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
KOG71551.1
Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.997
KOG67489.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
KOG76187.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.994
KOG68549.1
Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.993
KOG74329.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.992
KOG72638.1
Chloride transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.992
KOG71118.1
Menaquinone biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.992
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
    
 0.992
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
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