Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LA_0141Metal-dependent hydrolase of the beta-lactamase superfamily I. (312 aa)    
Predicted Functional Partners:
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.732
LA_3286
Adenylate cyclase related protein.
 
     0.677
LA_0288
Adenylate/guanylate cyclase.
 
     0.654
LA_0027
Adenylate/guanylate cyclase.
 
     0.613
cyaA
Adenylate/guanylate cyclase.
 
     0.583
CyaA18
Adenylate/guanylate cyclase.
 
     0.581
cyaA-9
Adenylate/guanylate cyclase.
 
     0.580
LA_2536
Adenylate/guanylate cyclase.
 
     0.578
LA_0993
Adenylate/guanylate cyclase.
 
     0.575
LA_2847
Response regulator with HD-GYP domain.
 
     0.575
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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