Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
fhlATranscriptional regulator. (699 aa)    
Predicted Functional Partners:
LA_3895
Histidine kinase sensor protein.
 
 
 
 0.836
rpoN
DNA-directed RNA polymerase sigma-54 subunit.
 
   
 0.795
LB_290
Histidine kinase sensor protein.
   
 
 0.756
LA_3894
Histidine kinase and response regulator hybrid protein.
 
 
 
 0.746
hfq
Host factor I related protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
  
 0.696
LA_1745
Histidine kinase and response regulator hybrid protein.
   
 
 0.682
LA_2541
Histidine kinase response regulator hybrid protein.
   
 
 0.673
LA_2223
Sensor histidine kinase of a two component response regulator.
 
 
 
 0.663
pldB
Lysophospholipase.
  
  
 0.643
LA_2676
Hypothetical protein.
     
 0.643
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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