Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_0791Transglycosylase. (749 aa)    
Predicted Functional Partners:
ftsI
Transpeptidase/penicillin binding protein.
 
  
 0.796
mreB
Actin-like ATPase involved in cell morphogenesis.
  
 
 
 0.748
rodA
Rod shape-determining protein; Belongs to the SEDS family.
 
   
 0.746
ftsI-2
Transpeptidase/penicillin binding protein.
 
  
 0.741
LA_0792
Hypothetical protein.
       0.731
gltA-2
Citrate synthase; Belongs to the citrate synthase family.
       0.702
LA_0788
SAM-dependent methyltransferase.
       0.660
spoU
rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.659
LA_0789
Predicted SAM-dependent methyltransferase.
       0.537
LA_3734
Cytoplasmic membrane protein.
 
   
 0.482
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
Server load: low (8%) [HD]