Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccmA-2ATP-binding protein of an ABC transporter complex. (330 aa)    
Predicted Functional Partners:
LA_0970
ABC transporter permease protein.
  
 0.984
LA_2113
Membrane protein of an ABC transporter complex.
  
 0.877
fabG-2
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.794
LA_0403
Permease component of an ABC transporter complex.
  
 
 0.527
LA_2463
ABC-type transport system involved in gliding motility.
  
 
 0.527
LA_4155
ABC transporter permease protein.
  
 
 0.527
LA_4289
ABC-type multidrug transport system, permease component.
  
  
 0.502
atpC
ATP synthase F1 sector epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
   0.486
atpD
F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 
 0.458
uup-3
ATPase component of ABC transporter.
   
 
 0.457
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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