Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vapCPilT-like protein. (132 aa)    
Predicted Functional Partners:
vagC
Virulence-associated protein VagC.
 
 
 0.997
LA_1816
Hypothetical protein.
   
   0.714
LA_0936
Hypothetical protein.
 
   
 0.649
LA_0812
Hypothetical protein.
   
 
 0.532
LA_1798
Phd-like protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.532
LA_1000
Hypothetical protein.
       0.531
mazE
Transcriptional regulator/antitoxin MazE.
     
 0.466
LA_1816a
Hypothetical protein.
 
   
 0.449
LA_3274
Predicted nucleic-acid-binding protein.
  
   
 0.430
LA_1003
Hypothetical protein.
       0.423
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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