Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
btuEGlutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)    
Predicted Functional Partners:
ggt
Gamma-glutamyltranspeptidase.
     
 0.911
btuE-2
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
 
0.911
LA_0595
Glutathione S-transferase-like protein.
   
 
 0.906
gst
Glutathione transferase.
   
 
 0.906
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
   
  
 0.582
ahpC
Peroxiredoxin.
   
 
 0.567
bcp
Peroxiredoxin.
  
  
 0.462
katE
Catalase; Belongs to the catalase family.
  
 
 0.445
LA_3664
Hypothetical protein.
  
 
 0.445
LA_0320
Thioredoxin.
   
 0.428
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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