Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LA_1963Outer membrane efflux protein. (468 aa)    
Predicted Functional Partners:
LA_1964
Multidrug efflux pump.
 
 
 0.903
LA_1966
Cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.893
LA_1963a
Multidrug efflux pump.
  
 
 0.865
LA_1965
Hypothetical protein.
       0.850
LA_3675
Hypothetical protein.
  
     0.756
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
      
 0.743
LA_1967
Cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.721
LA_1968
Hypothetical protein.
  
     0.714
LA_0425
Hypothetical protein.
  
     0.638
LA_1446
Heavy metal efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.580
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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