Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_1963aMultidrug efflux pump. (233 aa)    
Predicted Functional Partners:
LA_1964
Multidrug efflux pump.
      0.916
LA_1963
Outer membrane efflux protein.
  
 
 0.865
LA_1966
Cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.855
LA_1965
Hypothetical protein.
       0.812
LA_1962
Hypothetical protein.
       0.468
LA_1967
Cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.459
acrB
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.431
LA_3738
Acriflavine resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.431
LA_3740
Acriflavine resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.431
acrB-2
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.431
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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