Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LA_2012Sensory histidine kinase CreC. (441 aa)    
Predicted Functional Partners:
LA_2011
Response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain.
 
  0.994
creD
Inner membrane protein involved in colicin E2 resistance.
 
   
 0.846
LA_1745
Histidine kinase and response regulator hybrid protein.
  
 
 0.766
vicR
Response regulator.
  
   0.741
LA_0289
Adenylate/guanylate cyclase.
  
 
 0.732
ompR-2
Response regulator.
  
   0.726
LA_2423
Chemotaxis response regulator CheY.
  
   0.701
LA_3108
Response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain.
  
   0.699
baeS
Signal transduction histidine kinase.
  
     0.695
LA_3514
Serine/threonine phosphatase containing signal receiver domain REC.
 
 
 0.688
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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