Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LA_2109Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (107 aa)    
Predicted Functional Partners:
bolA
BolA family protein; Belongs to the BolA/IbaG family.
 
 
 0.984
LA_2108
Glutathione S-transferase.
  
  
 0.918
bolA-2
BolA family protein; Belongs to the BolA/IbaG family.
 
 
 0.879
gloB
Zn-dependent hydrolase.
 
  
 0.774
msrB
Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.
      
 0.768
ahpC
Peroxiredoxin.
  
 
 0.674
LA_4327
ferredoxin--NADP reductase.
  
 
 
 0.634
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
 
 0.573
map
Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.572
lpd-2
Dihydrolipoamide dehydrogenase.
  
 
 0.546
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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