Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LA_2113Membrane protein of an ABC transporter complex. (257 aa)    
Predicted Functional Partners:
ccmA-3
ATP-binding protein of an ABC transporter complex.
  
 0.982
ccmA-2
ATP-binding protein of an ABC transporter complex.
  
 0.877
bolA-2
BolA family protein; Belongs to the BolA/IbaG family.
       0.860
lpd-2
Dihydrolipoamide dehydrogenase.
       0.832
gloB
Zn-dependent hydrolase.
 
     0.714
ccmA-7
ATP-binding protein of an ABC transporter complex.
 
  
 0.597
LA_4214
Amino terminal protease.
  
  
 0.548
LA_2117
Anti-sigma factor antagonist.
       0.546
ccmA
ATP-binding protein of an ABC transporter complex.
  
  
 0.502
ccmA-4
ATP-binding protein of an ABC transporter complex.
  
  
 0.502
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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