Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_2170Lipoprotein with phospholipase D domain. (547 aa)    
Predicted Functional Partners:
LA_0635
S-layer-like protein.
 
    0.717
LA_2169
Lipoprotein.
 
      0.640
LA_2446
Hypothetical protein.
   
 0.629
LA_3734
Cytoplasmic membrane protein.
  
     0.626
LA_3848
Hypothetical protein.
  
 
 0.624
LA_2537
LipL45-related protein.
  
    0.622
LA_2196
Hypothetical protein.
  
    0.589
LA_1978
Hypothetical protein.
  
     0.587
LA_2459
SMC-like protein.
 
 
 0.585
LA_2167
Putative lipoprotein.
       0.578
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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