Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
LA_2182HIT family hydrolase. (129 aa)    
Predicted Functional Partners:
LA_2183
Hypothetical protein.
       0.748
tldD
Predicted Zn-dependent protease.
       0.710
tldD-2
Predicted Zn-dependent protease.
       0.709
glnA
Glutamine synthetase.
   
   0.628
LA_2188
ATPase.
       0.505
LA_2189
Conserved hypothetical protein.
       0.505
pbpC
Penicillin binding protein.
       0.484
lysU
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 0.461
sir2
Transcriptional regulator; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
    
  0.446
LA_2180
Hypothetical protein.
       0.409
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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