Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_2192Hypothetical protein. (249 aa)    
Predicted Functional Partners:
uvrD-3
DNA helicase UvrD.
       0.860
slpA
Peptidyl-prolyl cis-trans isomerase.
       0.860
LA_2191
Hypothetical protein.
       0.768
apbA
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.634
LA_2195
Hypothetical protein.
       0.563
LA_2900
Hypothetical protein.
 
     0.542
LA_1445
Outer membrane TolC superfamily protein.
  
     0.524
LA_2615
Conserved hypothetical protein.
  
     0.515
LA_4180
Putative aminotransferase.
 
     0.502
LA_4027
Hypothetical protein.
  
     0.491
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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