Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_2196Hypothetical protein. (789 aa)    
Predicted Functional Partners:
LA_2665
Flagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
    0.802
LA_1327
Anti-sigma factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
   0.790
LA_1295
Hypothetical protein.
  
    0.785
LA_0378
TPR-repeat-containing protein.
  
    0.784
LA_0289
Adenylate/guanylate cyclase.
 
  
 0.774
LA_0153
Hypothetical protein.
  
     0.773
LA_1100
Cytoplasmic membrane protein.
  
     0.773
LA_0675
Hypothetical protein.
  
     0.771
LA_0994
Hypothetical protein.
  
     0.771
LA_2772
cGMP-specific phosphodiesterase.
  
     0.771
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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