Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LA_2736acetyl-CoA carboxylase biotin carboxylase subunit. (487 aa)    
Predicted Functional Partners:
LA_2735
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit.
 
  
 0.996
LA_3803
acetyl-CoA carboxylase carboxyltransferase component.
 
 0.991
LA_2433
acetyl-CoA carboxylase carboxyltransferase component.
 
 0.989
ivd
isovaleryl-CoA dehydrogenase.
  
 0.919
LA_1130
acyl-CoA dehydrogenase.
  
 0.919
caiA-2
acyl-CoA dehydrogenase.
  
 0.919
caiA-5
acyl-CoA dehydrogenase.
  
 0.919
caiA-6
acyl-CoA dehydrogenase.
  
 0.919
LA_1424
3-oxoacid CoA-transferase.
  
 
 0.880
fabB
Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.862
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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