Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_2829Signal receiver component of two-component system. (152 aa)    
Predicted Functional Partners:
LA_2830
Histidine kinase sensor protein.
 
 
   0.971
LA_2828
Sensor histidine kinase and response regulator of a two component complex.
 
 
   0.898
LA_2827
Signal transduction protein containing REC and EAL domains.
  
 
 0.890
LA_1348
Histidine kinase sensor protein.
 
 
 0.849
LA_2533
Histidine kinase sensor protein.
 
 
   0.838
LA_2222
Sensor histidine kinase and response regulator of a two component complex.
 
 
 
 0.820
LA_1710
Histidine kinase sensor protein.
 
 
   0.818
LA_3894
Histidine kinase and response regulator hybrid protein.
 
 
 0.818
LA_4174
Histidine kinase sensor protein.
 
 
 0.817
LA_1746
Sensor histidine kinase and response regulator of a two component complex.
 
 
   0.803
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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