Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_3100Short-chain dehydrogenase. (295 aa)    
Predicted Functional Partners:
LA_3788
Putative hydrolase.
  
     0.617
LA_4245
Flavin-binding monooxygenase-like protein.
  
 
 0.560
LA_3897
Acyltransferase.
  
     0.555
fabG-2
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  0.536
LA_3156
Flavin-binding monooxygenase-like protein.
  
 
 0.527
LA_3362
Aminoglycoside phosphotransferase.
 
     0.525
LA_2584
Conserved hypothetical protein.
  
     0.498
caiA-2
acyl-CoA dehydrogenase.
  
 
  0.481
LA_3147
Alpha/beta hydrolase superfamily protein.
  
     0.481
LA_3664
Hypothetical protein.
  
 
 0.479
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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