STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LA_3113Serine/threonine kinase with GAF domain. (1731 aa)    
Predicted Functional Partners:
LA_0289
Adenylate/guanylate cyclase.
 
 
 0.914
LA_1745
Histidine kinase and response regulator hybrid protein.
 
 
 0.821
LA_2951
Two-component hybrid sensor and regulator.
  
 
 0.766
LA_2435
Serine/threonine phosphatase containing GAF domains.
 
 
0.743
LA_3858
Histidine kinase and response regulator hybrid protein.
 
 
 0.715
rsbW
Anti-sigma factor antagonist.
 
 
 0.687
ptc1
Serine/threonine phosphatase.
 
 
 0.671
LA_2094
FHA domain-containing protein.
  
 
 0.671
LA_2805
Histidine kinase sensor protein.
 
 0.658
LA_3114
Cytoplasmic membrane protein.
 
    0.656
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
Server load: low (24%) [HD]