Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
LA_3205Zn-dependent hydrolase. (340 aa)    
Predicted Functional Partners:
LA_3726
Putative lipoprotein.
      
 0.731
LB_225
Lipoprotein.
      
 0.731
LA_4114
Putative acetyl-CoA acetyltransferase.
  
  
 0.645
LA_2627
MaoC family protein.
 
    0.572
LA_2746
Hypothetical protein.
  
     0.434
LA_2689
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.432
LA_3472
Predicted nucleic-acid-binding protein.
  
     0.429
LA_4272
Hypothetical protein.
  
     0.427
LA_3206
Two-component response regulator receiver protein.
       0.418
LA_3207
Histidine kinase sensor protein.
       0.418
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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