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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LA_3206Two-component response regulator receiver protein. (135 aa)    
Predicted Functional Partners:
LA_3207
Histidine kinase sensor protein.
 
 
 0.953
cheA
Chemotaxis protein histidine kinase CheA.
  
 
 0.853
LA_2805
Histidine kinase sensor protein.
 
 
 
 0.838
LB_290
Histidine kinase sensor protein.
 
 
 
 0.837
LA_0133
Sensor histidine kinase of a two component response regulator.
 
 
 
 0.803
LA_3357
Histidine kinase sensor protein.
 
 
 
 0.800
LA_1528
Two-component response regulator.
  
 
 0.661
LA_1745
Histidine kinase and response regulator hybrid protein.
  
 
 0.657
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.576
cheA-2
Chemotaxis protein histidine kinase CheA.
  
 
 0.563
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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