Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LA_3206Two-component response regulator receiver protein. (135 aa)    
Predicted Functional Partners:
LA_3207
Histidine kinase sensor protein.
 
 
 
 0.952
LA_2805
Histidine kinase sensor protein.
 
 
 
 0.824
LB_290
Histidine kinase sensor protein.
 
 
 
 0.819
LA_0133
Sensor histidine kinase of a two component response regulator.
 
 
 
 0.802
LA_3357
Histidine kinase sensor protein.
 
 
 
 0.798
cheA
Chemotaxis protein histidine kinase CheA.
  
 
 0.697
LA_1745
Histidine kinase and response regulator hybrid protein.
  
 
 0.697
LA_1528
Two-component response regulator.
  
 
 0.639
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.568
fliP
Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.567
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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