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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LA_3207Histidine kinase sensor protein. (1165 aa)    
Predicted Functional Partners:
LA_1745
Histidine kinase and response regulator hybrid protein.
 
 
0.994
LA_3206
Two-component response regulator receiver protein.
 
 
 0.953
LA_3858
Histidine kinase and response regulator hybrid protein.
 
 
 0.903
LA_0289
Adenylate/guanylate cyclase.
  
 
 0.886
LA_2541
Histidine kinase response regulator hybrid protein.
 
 
 0.876
LA_2222
Sensor histidine kinase and response regulator of a two component complex.
 
0.849
LA_1432
Two-component response regulator receiver protein.
 
 
 0.834
LA_3514
Serine/threonine phosphatase containing signal receiver domain REC.
 
 
 
 0.826
LA_1186
Two-component response regulator.
 
 
 0.823
LA_1528
Two-component response regulator.
 
 
 0.811
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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