Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sufCATP-binding component of an ABC transporter complex. (255 aa)    
Predicted Functional Partners:
sufB
ABC transporter permease.
 0.999
LA_3562
ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 0.999
csdB
Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
  
 0.994
iscU
NifU-related protein.
 
  
 0.983
csdB-2
Selenocysteine lyase.
 
  
 0.948
paaD
Predicted metal-sulfur cluster biosynthetic enzyme.
 
  
 0.930
LA_1019
Hypothetical protein.
  
  
 0.860
nirD
Benzene 1,2-dioxygenase system ferredoxin component.
       0.860
LA_3022
Fe-S metabolism protein.
 
 
 0.834
LA_0589
Conserved hypothetical protein.
  
  
 0.557
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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