Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LA_3571Conserved hypothetical lipoprotein. (139 aa)    
Predicted Functional Partners:
LA_3267
Molybdopterin oxidoreductase iron-sulfur binding subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.969
cyoA
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.962
cyoC
Cytochrome c oxidase subunit III.
 
 
 0.899
LA_4027
Hypothetical protein.
 
 
 
 0.797
LA_3266
Fe-S-cluster-containing hydrogenase.
 
 
 
 0.784
cyoB
Cytochrome c oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
 
 0.760
LA_3263
Hypothetical protein.
 
 
 
 0.732
LA_3268
Hypothetical protein.
 
 
 
 0.670
LA_3507
Cytochrome c.
  
     0.630
LA_1896
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
   
  
 0.563
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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