Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LA_4286Conserved hypothetical protein; Belongs to the fructosamine kinase family. (296 aa)    
Predicted Functional Partners:
LA_4285
Predicted glycosyl hydrolase.
       0.712
wzb
Phosphotyrosine protein phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
     0.677
ccmA-7
ATP-binding protein of an ABC transporter complex.
       0.547
LA_4289
ABC-type multidrug transport system, permease component.
       0.547
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
   0.442
glpG
Intramembrane serine protease.
       0.402
LA_4287
ABC transporter ATP-binding protein.
       0.402
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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