node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BGO00_06355 | OJU56232.1 | BGO00_06355 | BGO00_09730 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
BGO00_06355 | OJU56466.1 | BGO00_06355 | BGO00_01355 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.980 |
BGO00_06355 | OJU57336.1 | BGO00_06355 | BGO00_04560 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
BGO00_06355 | OJU57546.1 | BGO00_06355 | BGO00_10530 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
BGO00_06355 | clpB | BGO00_06355 | BGO00_05165 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.980 |
BGO00_06355 | clpP | BGO00_06355 | BGO00_05045 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.739 |
BGO00_06355 | clpP-2 | BGO00_06355 | BGO00_07850 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.739 |
BGO00_06355 | groL | BGO00_06355 | BGO00_10085 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.999 |
BGO00_06355 | grpE | BGO00_06355 | BGO00_11690 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.999 |
BGO00_06355 | hrcA | BGO00_06355 | BGO00_11695 | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.960 |
OJU56232.1 | BGO00_06355 | BGO00_09730 | BGO00_06355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | 0.993 |
OJU56232.1 | OJU56466.1 | BGO00_09730 | BGO00_01355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease ATP-binding subunit ClpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.943 |
OJU56232.1 | OJU57546.1 | BGO00_09730 | BGO00_10530 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
OJU56232.1 | clpB | BGO00_09730 | BGO00_05165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.943 |
OJU56232.1 | clpP | BGO00_09730 | BGO00_05045 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.414 |
OJU56232.1 | clpP-2 | BGO00_09730 | BGO00_07850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.414 |
OJU56232.1 | groL | BGO00_09730 | BGO00_10085 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.943 |
OJU56232.1 | grpE | BGO00_09730 | BGO00_11690 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.848 |
OJU56232.1 | hrcA | BGO00_09730 | BGO00_11695 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.703 |
OJU56466.1 | BGO00_06355 | BGO00_01355 | BGO00_06355 | ATP-dependent Clp protease ATP-binding subunit ClpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | AAA family ATPase; Metagenomic; derived from metagenome: bioreactor metagenome; Belongs to the heat shock protein 70 family. | 0.980 |