node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJX57034.1 | OJX57827.1 | BGO89_11025 | BGO89_07610 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
OJX57034.1 | OJX61330.1 | BGO89_11025 | BGO89_01780 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
OJX57034.1 | OJX61351.1 | BGO89_11025 | BGO89_00355 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OJX57034.1 | gcvP | BGO89_11025 | BGO89_05670 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.866 |
OJX57034.1 | glyA | BGO89_11025 | BGO89_01450 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.827 |
OJX57034.1 | thyX | BGO89_11025 | BGO89_10825 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.693 |
OJX57290.1 | OJX57827.1 | BGO89_12455 | BGO89_07610 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
OJX57290.1 | OJX61330.1 | BGO89_12455 | BGO89_01780 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
OJX57290.1 | OJX61351.1 | BGO89_12455 | BGO89_00355 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
OJX57827.1 | OJX57034.1 | BGO89_07610 | BGO89_11025 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.648 |
OJX57827.1 | OJX57290.1 | BGO89_07610 | BGO89_12455 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.819 |
OJX57827.1 | OJX61330.1 | BGO89_07610 | BGO89_01780 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
OJX57827.1 | OJX61345.1 | BGO89_07610 | BGO89_01865 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GcvT family. | 0.436 |
OJX57827.1 | OJX61351.1 | BGO89_07610 | BGO89_00355 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.729 |
OJX57827.1 | gcvP | BGO89_07610 | BGO89_05670 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.761 |
OJX57827.1 | glyA | BGO89_07610 | BGO89_01450 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.437 |
OJX57827.1 | thyX | BGO89_07610 | BGO89_10825 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.432 |
OJX61175.1 | OJX61330.1 | BGO89_00875 | BGO89_01780 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.547 |
OJX61330.1 | OJX57034.1 | BGO89_01780 | BGO89_11025 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.648 |
OJX61330.1 | OJX57290.1 | BGO89_01780 | BGO89_12455 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.819 |