node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJY27065.1 | OJY28987.1 | BGP11_13195 | BGP11_17235 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.824 |
OJY27065.1 | OJY31964.1 | BGP11_13195 | BGP11_10420 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.716 |
OJY27065.1 | OJY36220.1 | BGP11_13195 | BGP11_07600 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.840 |
OJY27065.1 | fhs | BGP11_13195 | BGP11_03305 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. | 0.863 |
OJY27065.1 | folD | BGP11_13195 | BGP11_03290 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.537 |
OJY27065.1 | folD-2 | BGP11_13195 | BGP11_03295 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.537 |
OJY27065.1 | glyA | BGP11_13195 | BGP11_08770 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.716 |
OJY27065.1 | purU | BGP11_13195 | BGP11_18845 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.824 |
OJY28987.1 | OJY27065.1 | BGP11_17235 | BGP11_13195 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.824 |
OJY28987.1 | OJY31964.1 | BGP11_17235 | BGP11_10420 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.811 |
OJY28987.1 | OJY36220.1 | BGP11_17235 | BGP11_07600 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.822 |
OJY28987.1 | fhs | BGP11_17235 | BGP11_03305 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. | 0.863 |
OJY28987.1 | folD | BGP11_17235 | BGP11_03290 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.771 |
OJY28987.1 | folD-2 | BGP11_17235 | BGP11_03295 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.771 |
OJY28987.1 | glyA | BGP11_17235 | BGP11_08770 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.811 |
OJY28987.1 | purN | BGP11_17235 | BGP11_00815 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.847 |
OJY28987.1 | purU | BGP11_17235 | BGP11_18845 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.846 |
OJY31964.1 | OJY27065.1 | BGP11_10420 | BGP11_13195 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.716 |
OJY31964.1 | OJY28987.1 | BGP11_10420 | BGP11_17235 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.811 |
OJY31964.1 | OJY36220.1 | BGP11_10420 | BGP11_07600 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.716 |