STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIO03833.1Hypothetical protein. (190 aa)    
Predicted Functional Partners:
SIO03810.1
Hypothetical protein.
      
0.773
SIO03858.1
Hypothetical protein.
      
0.773
SIO03766.1
NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family.
       0.522
SIO03788.1
Hypothetical protein.
       0.522
SIO03740.1
Hypothetical protein.
       0.485
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
       0.437
Your Current Organism:
Fibrobacter sp. UWB11
NCBI taxonomy Id: 1896202
Other names: F. sp. UWB11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.