STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the folylpolyglutamate synthase family. (443 aa)    
Predicted Functional Partners:
OLA25663.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
   
 0.968
accA
acetyl-CoA carboxylase biotin carboxylase subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.908
OLA23836.1
NADH:flavin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.860
BHW17_09790
Cytosine permease; Frameshifted; too many ambiguous residues; incomplete; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.860
folE
GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.838
OLA25241.1
1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
   
 
  0.825
OLA25664.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.810
OLA25256.1
DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.810
OLA25242.1
PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.800
BHW17_08185
Vitamin B12 dependent methionine synthase activation subunit; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.757
Your Current Organism:
Dorea sp. 428
NCBI taxonomy Id: 1896999
Other names: D. sp. 42_8, Dorea sp. 42_8
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