STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB91641.1Ribosome biogenesis GTPase. (329 aa)    
Predicted Functional Partners:
SKC05867.1
Ribosome biogenesis GTPase.
  
  
 
0.907
SKC07377.1
Thiamine pyrophosphokinase.
  
 
 0.900
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
   0.838
rpsM
Small subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
    
   0.829
rpsI
Small subunit ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
   0.824
SKB66524.1
Small subunit ribosomal protein S15.
  
   0.810
SKB78180.1
Small subunit ribosomal protein S4.
  
 
   0.802
rpsG
Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.797
rpsU
SSU ribosomal protein S21P; Belongs to the bacterial ribosomal protein bS21 family.
   
   0.787
SKB73906.1
Small subunit ribosomal protein S16.
    
   0.784
Your Current Organism:
Lachnospiraceae bacterium
NCBI taxonomy Id: 1898203
Other names: L. bacterium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.