STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB95753.1Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (392 aa)    
Predicted Functional Partners:
SKB50893.1
Phosphoribosylformylglycinamidine synthase.
  
 
 0.999
SKB51080.1
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase.
 0.999
SKB50113.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.992
SKB78991.1
Phosphoribosylaminoimidazole-succinocarboxamide synthase.
 
 0.992
SKB95764.1
IMP cyclohydrolase.
 
  
 0.992
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.992
SKB51066.1
Phosphoribosylamine--glycine ligase.
 
 0.991
SKB59893.1
Glycine hydroxymethyltransferase.
  
 0.990
SKB50176.1
Amidophosphoribosyltransferase.
 
 0.987
SKB50106.1
Adenylosuccinate synthetase.
  
 0.986
Your Current Organism:
Lachnospiraceae bacterium
NCBI taxonomy Id: 1898203
Other names: L. bacterium
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