STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_0370KEGG: mmc:Mmcs_0360 hypothetical protein. (434 aa)    
Predicted Functional Partners:
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.891
Mkms_5027
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mmc:Mmcs_4939 ATP dependent DNA ligase.
   
 0.889
Mkms_5005
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mmc:Mmcs_4916 ATP dependent DNA ligase.
   
 0.869
Mkms_0854
KEGG: nfa:nfa29400 putative ATP-dependent DNA ligase.
   
 0.792
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.756
Mkms_0371
PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_0361 AMP-dependent synthetase and ligase.
       0.578
Mkms_0369
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mmc:Mmcs_0359 anti-sigma-factor antagonist.
       0.510
Mkms_4422
DNA-formamidopyrimidine glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: mmc:Mmcs_4336 DNA-formamidopyrimidine glycosylase; Belongs to the FPG family.
 
   
 0.492
Mkms_0280
PFAM: periplasmic binding protein; KEGG: mmc:Mmcs_0270 twin-arginine translocation pathway signal.
       0.468
Mkms_2704
KEGG: mmc:Mmcs_2659 hypothetical protein.
      
 0.455
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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