STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_0533Sodium/proton antiporter, CPA1 family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (533 aa)    
Predicted Functional Partners:
Mkms_0534
SMART: zinc finger, UBP-type protein; KEGG: mmc:Mmcs_0522 zinc finger, UBP-type.
     0.965
Mkms_0058
KEGG: mmc:Mmcs_0049 hypothetical protein.
   
 0.607
Mkms_0536
KEGG: mmc:Mmcs_0524 hypothetical protein.
       0.542
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 0.542
Mkms_0535
Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family.
       0.541
Mkms_0537
SMART: Rhodanese domain protein; KEGG: mmc:Mmcs_0525 rhodanese-like protein.
       0.509
Mkms_0539
KEGG: mmc:Mmcs_0527 hypothetical protein.
       0.509
Mkms_3606
PFAM: carbohydrate kinase, FGGY; KEGG: mmc:Mmcs_3533 carbohydrate kinase, FGGY; Belongs to the FGGY kinase family.
   
 0.494
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.494
Mkms_0135
KEGG: mmc:Mmcs_0126 hypothetical protein.
    
 0.449
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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