| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mkms_0514 | Mkms_2460 | Mkms_0514 | Mkms_2460 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.963 |
| Mkms_0514 | Mkms_2748 | Mkms_0514 | Mkms_2748 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: mmc:Mmcs_2704 fructose-bisphosphate aldolase. | 0.924 |
| Mkms_0514 | eno | Mkms_0514 | Mkms_4326 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.975 |
| Mkms_0514 | gpmA | Mkms_0514 | Mkms_0672 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.940 |
| Mkms_0514 | pgi | Mkms_0514 | Mkms_4420 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | PFAM: phosphoglucose isomerase (PGI); KEGG: mmc:Mmcs_4334 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.971 |
| Mkms_0514 | pgk | Mkms_0514 | Mkms_2451 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | PFAM: phosphoglycerate kinase; KEGG: mmc:Mmcs_2405 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.934 |
| Mkms_0514 | tal | Mkms_0514 | Mkms_2459 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.976 |
| Mkms_0514 | tpiA | Mkms_0514 | Mkms_2452 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.988 |
| Mkms_1956 | gpmA | Mkms_1956 | Mkms_0672 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_1910 D-3-phosphoglycerate dehydrogenase. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.926 |
| Mkms_2047 | gpmA | Mkms_2047 | Mkms_0672 | PFAM: glycerate kinase; KEGG: mmc:Mmcs_2001 glycerate kinase; Belongs to the glycerate kinase type-1 family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.906 |
| Mkms_2460 | Mkms_0514 | Mkms_2460 | Mkms_0514 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.963 |
| Mkms_2460 | Mkms_2748 | Mkms_2460 | Mkms_2748 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: mmc:Mmcs_2704 fructose-bisphosphate aldolase. | 0.933 |
| Mkms_2460 | eno | Mkms_2460 | Mkms_4326 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.951 |
| Mkms_2460 | gpmA | Mkms_2460 | Mkms_0672 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.867 |
| Mkms_2460 | pgi | Mkms_2460 | Mkms_4420 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: phosphoglucose isomerase (PGI); KEGG: mmc:Mmcs_4334 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.983 |
| Mkms_2460 | pgk | Mkms_2460 | Mkms_2451 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: phosphoglycerate kinase; KEGG: mmc:Mmcs_2405 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.836 |
| Mkms_2460 | tal | Mkms_2460 | Mkms_2459 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.999 |
| Mkms_2460 | tpiA | Mkms_2460 | Mkms_2452 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.952 |
| Mkms_2748 | Mkms_0514 | Mkms_2748 | Mkms_0514 | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: mmc:Mmcs_2704 fructose-bisphosphate aldolase. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.924 |
| Mkms_2748 | Mkms_2460 | Mkms_2748 | Mkms_2460 | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: mmc:Mmcs_2704 fructose-bisphosphate aldolase. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.933 |