Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_1237PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_1220 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)    
Predicted Functional Partners:
Mkms_2509
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: mmc:Mmcs_2464 glucose-methanol-choline oxidoreductase.
  
 
 0.916
Mkms_2507
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_2462 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.913
Mkms_2320
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_2273 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.907
Mkms_1235
PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_1218 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.641
Mkms_1236
PFAM: regulatory protein, AsnC/Lrp family; KEGG: mmc:Mmcs_1219 transcriptional regulator, AsnC family.
  
  
 0.602
kgd
2-oxoglutarate dehydrogenase E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate ( [...]
  
 0.572
Mkms_1539
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_1516 3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein.
  
 0.543
Mkms_4579
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_4492 3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein.
  
 0.543
Mkms_0391
PFAM: Lactate/malate dehydrogenase; KEGG: mmc:Mmcs_0382 lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.535
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.534
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.