STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_1622PFAM: bifunctional deaminase-reductase domain protein; KEGG: mmc:Mmcs_1598 bifunctional deaminase-reductase-like protein. (188 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.649
Mkms_1623
KEGG: mmc:Mmcs_1599 hypothetical protein.
       0.618
Mkms_3399
KEGG: mmc:Mmcs_3337 DNA-binding protein.
 
     0.470
Mkms_1626
TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: mmc:Mmcs_1602 Dyp-type peroxidase.
     
 0.448
Mkms_3376
PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: mmc:Mmcs_3314 hypothetical protein.
 
    0.433
Mkms_1624
PFAM: PepSY-associated TM helix domain protein; KEGG: mmc:Mmcs_1600 PepSY-associated TM helix.
       0.424
Mkms_1621
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_1597 alcohol dehydrogenase, zinc-binding protein.
  
  
 0.422
Mkms_1625
PFAM: protein of unknown function DUF461; KEGG: mmc:Mmcs_1601 protein of unknown function DUF461.
       0.410
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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