Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_1663PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_1637 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (486 aa)    
Predicted Functional Partners:
Mkms_1658
PFAM: dihydrodipicolinate synthetase; KEGG: mmc:Mmcs_1632 dihydrodipicolinate synthetase; Belongs to the DapA family.
  
 
 0.911
Mkms_1654
1-hydroxy-2-naphthoate dioxygenase / gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein; KEGG: mmc:Mmcs_1628 cupin 2, conserved barrel.
     
 0.902
Mkms_0521
PFAM: iron-containing alcohol dehydrogenase; KEGG: mmc:Mmcs_0510 iron-containing alcohol dehydrogenase.
  
 0.663
Mkms_4786
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_4700 acetoacetyl-CoA synthase.
  
 0.614
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.614
Mkms_2046
PFAM: copper amine oxidase; KEGG: mmc:Mmcs_2000 amine oxidase (copper-containing).
  
 0.599
Mkms_1580
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mmc:Mmcs_1556 amine oxidase (flavin-containing).
   
 0.583
kgd
2-oxoglutarate dehydrogenase E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate ( [...]
  
 0.572
Mkms_1661
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: mmc:Mmcs_1635 fumarate reductase/succinate dehydrogenase flavoprotein-like protein.
  
 0.566
Mkms_1732
KEGG: mmc:Mmcs_1704 NAD-dependent aldehyde dehydrogenases-like protein.
  
     0.555
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.