STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_2361PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; SMART: AAA ATPase; KEGG: mmc:Mmcs_2314 adenylate/guanylate cyclase. (1473 aa)    
Predicted Functional Partners:
Mkms_0360
KEGG: mmc:Mmcs_0350 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; protein phosphatase 2C domain protein.
 
 
 0.982
Mkms_5245
PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: mmc:Mmcs_5156 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.961
Mkms_3658
PFAM: GAF domain protein; KEGG: mmc:Mmcs_3585 putative GAF sensor protein.
  
 
 0.940
Mkms_1085
PFAM: cyclic nucleotide-binding; ATP-binding region, ATPase domain protein domain protein; KEGG: mmc:Mmcs_1069 cyclic nucleotide-binding protein.
 0.901
Mkms_2261
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mmc:Mmcs_2215 diguanylate cyclase/phosphodiesterase.
  
 0.807
Mkms_2359
PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_2312 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.795
Mkms_1253
Putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mmc:Mmcs_1236 adenylate/guanylate cyclase.
 
  
 0.775
Mkms_2535
PFAM: cyclic nucleotide-binding; KEGG: mmc:Mmcs_2490 cyclic nucleotide-binding protein.
 
 0.741
Mkms_1795
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: mmc:Mmcs_1748 diguanylate cyclase/phosphodiesterase with GAF sensor.
 
 
 0.739
Mkms_4370
PFAM: GCN5-related N-acetyltransferase; cyclic nucleotide-binding; KEGG: mmc:Mmcs_4284 cyclic nucleotide-binding protein.
 
 0.704
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.