STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_2950Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: mmc:Mmcs_2906 periplasmic sensor signal transduction histidine kinase. (379 aa)    
Predicted Functional Partners:
Mkms_2949
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_2905 two component transcriptional regulator, winged helix family.
 
 0.974
Mkms_3658
PFAM: GAF domain protein; KEGG: mmc:Mmcs_3585 putative GAF sensor protein.
 
 
 0.900
Mkms_1457
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_1439 two component transcriptional regulator, winged helix family.
 
 0.893
mprA
Two component transcriptional regulator, winged helix family; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity).
 
 0.890
Mkms_0723
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_0709 two component transcriptional regulator, winged helix family.
 
 0.880
Mkms_0174
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_0165 two component transcriptional regulator, winged helix family.
 
 0.877
Mkms_1365
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_1347 two component transcriptional regulator, winged helix family.
 
 0.875
Mkms_4535
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_4448 two component transcriptional regulator, winged helix family.
 
 0.875
Mkms_4000
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_3926 two component transcriptional regulator, winged helix family.
 
 0.873
Mkms_4678
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_4590 two component transcriptional regulator, winged helix family.
 
 0.871
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.