node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mkms_3319 | Mkms_3324 | Mkms_3319 | Mkms_3324 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | 0.995 |
Mkms_3319 | Mkms_3325 | Mkms_3319 | Mkms_3325 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | 0.846 |
Mkms_3319 | ftsZ | Mkms_3319 | Mkms_3315 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.957 |
Mkms_3319 | mraZ | Mkms_3319 | Mkms_3327 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: mmc:Mmcs_3265 protein of unknown function UPF0040; Belongs to the MraZ family. | 0.705 |
Mkms_3319 | murC | Mkms_3319 | Mkms_3317 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.994 |
Mkms_3319 | murD | Mkms_3319 | Mkms_3320 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.981 |
Mkms_3319 | murE | Mkms_3319 | Mkms_3323 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.979 |
Mkms_3319 | murF | Mkms_3319 | Mkms_3322 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.989 |
Mkms_3319 | murG | Mkms_3319 | Mkms_3318 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.996 |
Mkms_3319 | rsmH | Mkms_3319 | Mkms_3326 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.854 |
Mkms_3324 | Mkms_3319 | Mkms_3324 | Mkms_3319 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: mmc:Mmcs_3257 cell division protein FtsW; Belongs to the SEDS family. | 0.995 |
Mkms_3324 | Mkms_3325 | Mkms_3324 | Mkms_3325 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | 0.968 |
Mkms_3324 | ftsZ | Mkms_3324 | Mkms_3315 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.921 |
Mkms_3324 | mraZ | Mkms_3324 | Mkms_3327 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: mmc:Mmcs_3265 protein of unknown function UPF0040; Belongs to the MraZ family. | 0.804 |
Mkms_3324 | murC | Mkms_3324 | Mkms_3317 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.973 |
Mkms_3324 | murD | Mkms_3324 | Mkms_3320 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.962 |
Mkms_3324 | murE | Mkms_3324 | Mkms_3323 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.964 |
Mkms_3324 | murF | Mkms_3324 | Mkms_3322 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.964 |
Mkms_3324 | murG | Mkms_3324 | Mkms_3318 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.977 |
Mkms_3324 | rsmH | Mkms_3324 | Mkms_3326 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: mmc:Mmcs_3262 peptidoglycan glycosyltransferase. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.947 |