node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mkms_2530 | Mkms_2532 | Mkms_2530 | Mkms_2532 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.994 |
Mkms_2530 | Mkms_3366 | Mkms_2530 | Mkms_3366 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobinamide kinase; PFAM: cobalbumin biosynthesis enzyme; KEGG: mmc:Mmcs_3304 cobalbumin biosynthesis enzyme. | 0.905 |
Mkms_2530 | Mkms_3404 | Mkms_2530 | Mkms_3404 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: mmc:Mmcs_3342 phosphoglycerate mutase. | 0.454 |
Mkms_2530 | cobB | Mkms_2530 | Mkms_2119 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.902 |
Mkms_2530 | cobD | Mkms_2530 | Mkms_3411 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.794 |
Mkms_2530 | cobQ | Mkms_2530 | Mkms_2097 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.906 |
Mkms_2530 | cobS | Mkms_2530 | Mkms_3368 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.774 |
Mkms_2530 | cobT | Mkms_2530 | Mkms_3367 | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.872 |
Mkms_2532 | Mkms_2530 | Mkms_2532 | Mkms_2530 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: mmc:Mmcs_2485 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.994 |
Mkms_2532 | Mkms_3366 | Mkms_2532 | Mkms_3366 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide kinase; PFAM: cobalbumin biosynthesis enzyme; KEGG: mmc:Mmcs_3304 cobalbumin biosynthesis enzyme. | 0.852 |
Mkms_2532 | Mkms_3404 | Mkms_2532 | Mkms_3404 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: mmc:Mmcs_3342 phosphoglycerate mutase. | 0.480 |
Mkms_2532 | Mkms_4807 | Mkms_2532 | Mkms_4807 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: mmc:Mmcs_4721 Cob(II)yrinic acid a,c-diamide reductase. | 0.487 |
Mkms_2532 | cobB | Mkms_2532 | Mkms_2119 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.933 |
Mkms_2532 | cobD | Mkms_2532 | Mkms_3411 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.889 |
Mkms_2532 | cobQ | Mkms_2532 | Mkms_2097 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
Mkms_2532 | cobS | Mkms_2532 | Mkms_3368 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.978 |
Mkms_2532 | cobT | Mkms_2532 | Mkms_3367 | KEGG: mmc:Mmcs_2487 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.816 |
Mkms_3365 | Mkms_3366 | Mkms_3365 | Mkms_3366 | KEGG: mmc:Mmcs_3303 hypothetical protein. | Adenosylcobinamide kinase; PFAM: cobalbumin biosynthesis enzyme; KEGG: mmc:Mmcs_3304 cobalbumin biosynthesis enzyme. | 0.854 |
Mkms_3365 | cobS | Mkms_3365 | Mkms_3368 | KEGG: mmc:Mmcs_3303 hypothetical protein. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.854 |
Mkms_3365 | cobT | Mkms_3365 | Mkms_3367 | KEGG: mmc:Mmcs_3303 hypothetical protein. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.854 |