STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_3919PFAM: beta-lactamase domain protein; KEGG: mmc:Mmcs_3845 beta-lactamase-like protein. (257 aa)    
Predicted Functional Partners:
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.880
Mkms_3917
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.844
Mkms_3922
KEGG: mmc:Mmcs_3848 cysteine synthases; TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
       0.757
Mkms_3923
Molybdopterin synthase subunit MoaD; PFAM: thiamineS protein; KEGG: mmc:Mmcs_3849 thiamineS.
       0.757
Mkms_3924
PFAM: Mov34/MPN/PAD-1 family protein; KEGG: mmc:Mmcs_3850 Mov34/MPN/PAD-1.
  
    0.731
Mkms_3925
PFAM: peptidase S58, DmpA; KEGG: mmc:Mmcs_3851 peptidase S58, DmpA.
       0.689
Mkms_3926
KEGG: mmc:Mmcs_3852 hypothetical protein.
       0.689
clpS
ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.684
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.665
Mkms_3928
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.664
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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