STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_4225PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mmc:Mmcs_4150 alpha/beta hydrolase fold-3. (350 aa)    
Predicted Functional Partners:
Mkms_4224
KEGG: mmc:Mmcs_4149 cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
  
 0.860
Mkms_4226
PFAM: lipolytic enzyme, G-D-S-L family; KEGG: mmc:Mmcs_4151 lipolytic enzyme, G-D-S-L.
  
  
 0.707
Mkms_0211
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mmc:Mmcs_0202 alpha/beta hydrolase fold-3.
  
   
 0.653
Mkms_4227
KEGG: mmc:Mmcs_4152 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.625
Mkms_3181
PFAM: beta-lactamase; KEGG: mmc:Mmcs_3120 beta-lactamase.
  
  
 0.566
Mkms_3374
KEGG: mmc:Mmcs_3312 hypothetical protein.
   
 0.550
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
  
 
 0.502
Mkms_3534
PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_3471 AMP-dependent synthetase and ligase.
  
  
 0.494
Mkms_4223
KEGG: mmc:Mmcs_4148 hypothetical protein.
       0.479
Mkms_3729
PFAM: amidohydrolase 2; KEGG: mmc:Mmcs_3656 amidohydrolase 2.
  
  
 0.477
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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