Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mkms_4635KEGG: mmc:Mmcs_4548 hypothetical protein. (774 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
     
 0.533
Mkms_4634
Sodium/proton antiporter, CPA1 family; PFAM: sodium/hydrogen exchanger; KEGG: mmc:Mmcs_4547 sodium/hydrogen exchanger; TC 2.A.36.
       0.510
Mkms_4631
PFAM: Abortive infection protein; KEGG: mmc:Mmcs_4544 abortive infection protein.
       0.506
Mkms_4632
KEGG: mmc:Mmcs_4545 hypothetical protein.
       0.506
Mkms_1458
PFAM: NLP/P60 protein; KEGG: mmc:Mmcs_1440 NLP/P60.
  
  
 0.486
Mkms_1465
PFAM: NLP/P60 protein; KEGG: mmc:Mmcs_1447 NLP/P60.
  
  
 0.486
Mkms_2496
PFAM: NLP/P60 protein; KEGG: mmc:Mmcs_2451 NLP/P60.
  
  
 0.486
Mkms_3624
TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: mmc:Mmcs_3551 ribonuclease, Rne/Rng family.
  
  
 0.446
Mkms_0876
KEGG: mmc:Mmcs_0859 hypothetical protein.
  
    0.428
Mkms_3644
KEGG: mmc:Mmcs_3571 putative lipoprotein.
  
    0.428
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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