STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mkms_5066TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: mmc:Mmcs_4978 protein of unknown function UPF0025. (172 aa)    
Predicted Functional Partners:
Mkms_5065
KEGG: mmc:Mmcs_4977 hypothetical protein.
 
     0.809
Mkms_5067
KEGG: mmc:Mmcs_4979 hypothetical protein.
       0.773
Mkms_3917
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.755
zwf-3
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
       0.695
Mkms_5068
PFAM: cutinase; KEGG: mmc:Mmcs_4980 cutinase.
     
 0.570
Mkms_2139
PFAM: metallophosphoesterase; KEGG: mmc:Mmcs_2093 metallophosphoesterase.
     
 0.462
Mkms_0977
KEGG: mmc:Mmcs_0959 hypothetical protein.
 
 
 
 0.446
Mkms_1620
PFAM: putative esterase; KEGG: mmc:Mmcs_1596 putative esterase.
  
  
 0.438
Mkms_2817
PFAM: putative esterase; KEGG: mmc:Mmcs_2773 putative esterase.
  
  
 0.438
Mkms_5103
PFAM: putative esterase; KEGG: mmc:Mmcs_5015 putative esterase.
  
  
 0.438
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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