STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sppFMonooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)    
Predicted Functional Partners:
sppH
Protein in whiE locus; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.797
sppD
Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.786
sppE
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.764
sppG
Protein in whiE locus; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.747
sppB
Polyketide beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
    0.737
sppA
beta-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
    0.701
sppC
Curamycin polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.693
ANW21639.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.505
ANW19742.1
M6 family metalloprotease domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.490
ANW17515.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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